Thalassaemia is an inheriting blood disorder that can cause mild to severe anemia.
Thalassaemia involves problems with the production of hemoglobin in red blood cells. As a result, a person with the Thalassaemia doesn’t have enough hemoglobin or red blood cells to carry Oxygen throughout the body (anemia).
The signs and symptoms of Thalassaemia are:
Fatigue (feeling tired) and weakness;
Pale skin or jaundice (yellowing of the skin);
Protruding abdomen, with enlarged spleen and liver;
Dark urine; and
Abnormal facial bones and poor growth.
Haemophilia is a blood condition in which an essential clotting factor is either partly or completely missing. This causes a person with haemophilia to bleed for longer than normal. Cuts and grazes are not great problems as a little pressure and a plaster are usually enough to stop bleeding. The main problem is internal bleeding into joints, muscles and soft tissues. Haemophilia is a lifelong inherited genetic condition, which affects females as carriers and males who inherit the condition. About a third of new diagnoses are where there is no previous family history.
It appears world-wide and occurs in all racial groups. About 6,000 people are affected with haemophilia in the UK. There are two types of haemophilia, the most common being haemophilia A, in which Factor VIII is lacking. In haemophilia B, Factor IX is lacking. People with severe haemophilia can experience spontaneous bleeding usually into the joints. If left untreated these bleeds cause acute pain and severe joint damage leading to disability. Bleeding episodes have in the past caused difficulties with education and employment, as well as mobility problems for many who have been crippled by the effects of regular bleeding into joints.
Leukaemia literally means 'many white cells in the blood'. The white cells are part of the body’s immune system, and there are several sub-groups of white cells that have different sorts of roles in recognising and dealing with ‘invaders’ such as bacteria and viruses as well as other types of foreign protein.
All of the blood cells originate in the bone marrow and leukaemia (blood cancer) is a disease where the bone marrow produces large numbers of abnormal white cells. This means that the normal marrow is pushed into smaller and smaller areas. This results in fewer normal cells being produced and gives rise to some of the symptoms. Chronic leukaemia is a slowly progressive form of leukaemia and tends to involve more mature cell types. It may not need treatment immediately, but if treatment is required it is usually chemotherapy, given in the form of tablets.
The signs and symptoms of Chronic Leukaemia or Blood Cancer are:
tiredness (due to anaemia);
bruising easily (often without having had any blow or fall);
enlarged lymph glands;
night sweats; and